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Getting going in a recession is tough, and who says it easy is not being truthful, said Cynvenio CEO Andr de Fusco. Cynvenio operated frugally, and employees agreed to work on commissions even though it made life difficult for them, de Fusco said.

Cynvenio developed a biopsy technology that detects early stage cancer cells in blood. The company now has 26 employees and is moving into its commercial stage.

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The dream is coming to fruition, said Tom Dwyer, a senior vice president for commercial real estate company CBRE Inc.

starting to see more and more interest gained in this area in part because of Omega Speedmaster Vintage

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Is the Conejo Valley morphing into Valley in the industry, including the head of the Westlake Village based nonprofit group Bio Science Alliance, have identified propitious signs that it is. The alliance formed in 2007 to develop a life science cluster along the Highway 101 corridor.

And Amgen announced last month that it had spun off a new drug development company, Atara Biotherapeutics, which could be the first of more locally based Amgen spinoffs.

The Atara deal could be just the tip Omega Speedmaster 3513.33

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Kythera people said, 'We are a very well known management team, we have no interest in moving, Reinke said. By doing so, Kythera also paved the way for others to follow suit.

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California has committed resources to develop the industry, and the state may be the largest hub in the nation, said CSUCI Vice President and Provost Dawn Neuman. major clusters include San Francisco, San Diego and Los Angeles, and we right in the middle of all that, she said.

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The county educational institutions have also recognized the opportunity, and California Lutheran University and CSU Channel Islands are positioning graduates for the jobs.

reality is setting in that this is hopefully the next up and coming hub in California for biotech, he said.

conditions are appropriate, we could look to support the creation of other biotechs in the area, she said in an email, adding that the company believes County offers a quality standard of living and is an ideal location for other biotechs. said it would make it easier for Amgen to recruit new hires if a vibrant life sciences sector existed in the region. Among other pluses, the local labor and talent pool would be larger.

The fact that a well known venture capital firm is involved is a good sign for Atara, Reinke said.

´╗┐Conejo Valley sees signs of becoming biotech mecca

of the iceberg. Compared with his predecessors, Amgen CEO Bob Bradway is more inclined to license out intellectual property to companies that agree to keep a local presence, Reinke said.

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don track it nearly as closely as Brent (Reinke) and others, he said. I track people and see people leaving Amgen either because they retiring and stay in the area, or they create companies. And I see that quite often. So I think that a sign that things are going to grow.

Conejo Boulevard by 28,185 feet, bringing the total square footage to 277,800, according to a spokesman with the city of Thousand Oaks.

Kythera went public in October. Leonard didn return a phone call seeking comment.

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Amgen spokeswoman Kristen Davis said the company is about such deals.

you look at the educational base, historically in Ventura County it wasn really strong in biotech, but now CLU and CSUCI are starting to grasp that, Dwyer said.

The company has a new lab in Westlake Village, and de Fusco said significant announcements will come by the first of the year.

In 2005, Kythera Biopharmaceuticals Inc. in Calabasas was founded by Keith Leonard, who previously worked as a vice president and general manager of Europe for Amgen. Reinke said Leonard and his team stood their ground when investors pushed for them to move to the Bay Area.

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In 2007, after Amgen laid off 675 local employees, a number of scientists and others seeking to remain in the area joined or launched companies nearby. Some of those companies went belly up after the recession. But Cynvenio Biosystems in Westlake Village survived after forming in January 2008 with a small group of people, many from Amgen.

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of our students, said professor Dennis Revie, chairman of CLU biology department, rather work in industry than in health care or at research universities. said another sign of the industry growing is construction at drug and medical device maker Baxter International Inc.

the intellectual talent, said alliance Chairman Brent Reinke. companies are getting creative about how they raise money, with a lot coming from outside the region. investors with Omega Constellation Vintage Ladies ties to Amgen scientists are becoming particularly interested, he said.

He could not say if the Conejo Valley will end up as a biotech version of Silicon Valley, but he, too, is seeing the signs.

Baxter is headquartered in Deerfield, Ill., but has an office in Westlake Village and a plant in Thousand Oaks. It expanding the plant on Rancho Omega Seamaster 007 Professional

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Talk of a biotech hub forming in the Conejo Valley has gone on for at least two years and was recently rejuvenated by Amgen announcement that it had spun off a company that will maintain a local presence.

also know people who left eight to nine years ago and now they looking to come back to the Thousand Oaks Camarillo area, and I hear that quite a bit directly.

The biotech giant teamed with a Silicon Valley venture capital firm, Kleiner Perkins Caufield Byers, to form Atara, which will have licenses to six Amgen drugs in various stages of development. The financial terms weren disclosed, but Reinke said the deal requires that Atara keep a location near Amgen Thousand Oaks campus.

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